Methylation Pack

Physician-formulated daily methylation support — homocysteine regulation, one-carbon metabolism cofactors, and glutathione pathway support in one pouch.

Methylation is one of the body's most fundamental biochemical processes — involved in DNA regulation, neurotransmitter synthesis, detoxification, and homocysteine metabolism. Efficient one-carbon metabolism keeps these pathways running cleanly; when it's inefficient, homocysteine can build up and impair both vascular and neurological function.

The Methylation Pack was built by a physician to support this pathway directly — bioactive methylated B-vitamins, the mineral cofactors methylation enzymes require, and glutathione pathway support alongside it.

📋 Clinical Note

The methylation cycle converts homocysteine back to methionine using methylated folate (5-MTHF) and methylcobalamin (B12) as cofactors, with B6 supporting the alternative transsulfuration pathway that converts homocysteine to cysteine and, ultimately, glutathione. NAC directly supplies this transsulfuration pathway with a glutathione precursor. Magnesium is a required cofactor for SAM-dependent methyltransferase enzymes throughout the body. Trace minerals, particularly zinc and selenium, support additional methylation-related enzymatic activity. Vitamin D and K2 (via the ADEK complex) and omega-3 fatty acids round out the formula with complementary metabolic and anti-inflammatory support.

🧬 What Happens When Methylation Is Inefficient

• ⚠️ Homocysteine can build up — impairing vascular elasticity and increasing cardiovascular risk markers
• ⚠️ Neurotransmitter synthesis slows — methylation is required for producing several key neurotransmitters
• ⚠️ Standard folic acid and B12 aren't always usable — many people have reduced ability to convert these to their active, methylated forms
• ⚠️ The transsulfuration pathway needs support too — not just remethylation, but the route to glutathione production
• ⚠️ Magnesium is a hidden requirement — methylation enzymes throughout the body depend on it as a cofactor

Methylation runs quietly in the background of nearly every cell. This pack supports it directly, not just the downstream symptoms of when it's not working.

💊 Your Daily Support Pouch Contains

🌿 Methyl B-Complex

• 5-MTHF (400mcg DFE) and Methylcobalamin B12 (500mcg) — the pre-methylated, bioactive forms that drive homocysteine remethylation
• B6 (10mg) supports the alternative transsulfuration pathway
• Full panel: B1 20mg, B2 17mg, B3 75mg total, Biotin 300mcg, Pantothenic Acid 50mg
• Vegan Capsule (Hypromellose), MCT 70% C8/C10 Coconut on Acacia | Free from: Animal Products, Wheat, Soy, Peanuts, Tree Nuts, Eggs, Milk, Shellfish, Sesame, Fish

🌿 NAC (N-Acetyl Cysteine) — 600mg

• Directly supplies the transsulfuration pathway with a glutathione precursor
• Capsule: Hypromellose (Natural Vegetable), Rice Bran | Contains: Rice | Free from: Dairy, Wheat, Soy, Peanuts, Tree Nuts, Eggs, Shellfish, Sesame, Fish

🌿 Magnesium Glycinate — 133mg

• Required cofactor for SAM-dependent methyltransferase enzymes throughout the body
• Capsule: Hypromellose (Vegetable), Microcrystalline Cellulose, Magnesium Stearate, Silica, Stearic Acid | Free from: Artificial Colors or Flavors, Dairy, Wheat, Soy, Peanuts, Tree Nuts, Eggs, Shellfish, Sesame, Fish

🌿 Trace Minerals — Full Panel

• Iodine, Zinc, Selenium, Copper, Manganese, Chromium, Molybdenum, Potassium, Boron, Vanadium, Silica
• Zinc and selenium support additional methylation-related enzymatic activity
• Capsule type not specified on manufacturer label | Free from: Dairy, Wheat, Soy, Peanuts, Tree Nuts, Eggs, Shellfish, Sesame, Fish

🌿 ADEK Complex — Vitamin A, D3, E, Dual K2

• Vitamin D3 (125mcg/5,000 IU) and dual-form K2 for complementary metabolic support
• Capsule: Hypromellose with Rice Flour, Rice Fiber, Rice Extract | Free from: Artificial colors/flavors, Dairy, Preservatives, Wheat, Soy, Peanuts, Tree Nuts, Eggs, GMOs, Shellfish, Sesame, Fish
• Warning: Vitamin K may interact with blood-thinning medications — consult your physician if applicable

🌿 Omega-3 — 1000mg Fish Oil (EPA + DHA)

• Complementary anti-inflammatory support alongside methylation pathway function
• Softgel: Gelatin with Carob color, Vegetable Glycerin, Purified Water | Contains: Fish
• ⚠️ Not vegan — this is the one ingredient in this pack that differs from our other vegetable-capsule formulations. Gelatin source is not specified on the manufacturer label; halal/kosher status requires confirmation before certification claims can be made.

⚡ Four Pillars of Methylation Support

• ✅ Homocysteine remethylation — Methylated 5-MTHF and B12 drive the primary methylation cycle
• ✅ Transsulfuration and glutathione — B6 + NAC support the alternative pathway to glutathione
• ✅ Enzymatic cofactor support — Magnesium + Trace Minerals supply what methylation enzymes require
• ✅ Complementary metabolic support — ADEK + Omega-3 round out the formula

💡 Why This Stack Works Synergistically

These six formulations support the methylation cycle from both branches:

• Methyl B-Complex → homocysteine remethylated back to methionine using pre-activated, bioactive cofactors
• NAC → the transsulfuration branch supplied directly with a glutathione precursor
• Magnesium + Trace Minerals → the enzymatic cofactors methylation reactions depend on, throughout the body
• ADEK + Omega-3 → complementary metabolic and anti-inflammatory support

This isn't a basic B12 gummy. This isn't guesswork.

This is physician-formulated methylation support — addressing both branches of homocysteine metabolism, not just one.

🔬 Full Transparency — Verified Supplement Facts

• ✅ No proprietary blends — every dose verified and disclosed
• ✅ Physician-formulated — not assembled by a marketing team
• ✅ 5 of 6 ingredients use vegetable-based capsules — no gelatin, no animal-derived shells
• ⚠️ Omega-3 is the exception — gelatin softgel, contains fish. Not vegan. Halal/kosher status pending gelatin source confirmation.
• ✅ Free from (except Omega-3): Wheat, Soy, Dairy, Peanuts, Tree Nuts, Eggs, Shellfish, Sesame, GMOs, Artificial Colors & Flavors
• ✅ cGMP certified facility — manufactured to pharmaceutical standards
• ✅ Third-party tested — purity and potency verified

🕌 Dietary & Religious Compliance

Five of six formulations in this pack use vegetable-based capsules with zero animal-derived gelatin. The Omega-3 softgel is the exception — gelatin source not specified on label, contains fish. This means the pack cannot currently be certified vegan, and halal/kosher status depends on confirming the gelatin's origin with the manufacturer.

We believe in disclosing this clearly rather than making a claim we can't fully back. Always consult your religious authority for final certification guidance.

⚠️ Suggested Use

Take all capsules in your daily pouch each morning, preferably with or after breakfast. Consult your healthcare provider before starting any supplement regimen, especially if you are taking blood-thinning medication, have known MTHFR gene variants, or are managing a medical condition.

🏆 Perfect For

• Individuals with known MTHFR gene variants who need pre-methylated B-vitamins
• Anyone whose bloodwork has shown elevated homocysteine
• Those interested in supporting detoxification, neurotransmitter synthesis, and cardiovascular health through methylation pathway support
• Note: pescatarians are fine with this pack; strict vegans or those requiring certified halal/kosher gelatin should contact us before ordering

📦 Pack Details

• ✅ 6 formulations per daily pouch
• ✅ 30-day supply — one pouch per day
• ✅ AM delivery recommended — take with or after breakfast
• ✅ 80% less plastic than traditional supplement bottles
• ✅ Ships from Las Vegas, NV in 2–5 business days
• ✅ Eco-friendly packaging — physician-branded, professionally labeled

Science-backed. Physician-formulated. Fully transparent. Pouch-delivered.

Tear. Take. Feel the difference. 💪