{"product_id":"methylation-pack","title":"Methylation Pack","description":"\u003c!-- METHYLATION PACK — SHOPIFY HTML DESCRIPTION --\u003e\n\n\u003cp\u003e\u003cstrong\u003ePhysician-formulated daily methylation support — homocysteine regulation, one-carbon metabolism cofactors, and glutathione pathway support in one pouch.\u003c\/strong\u003e\u003c\/p\u003e\n\n\u003chr\u003e\n\n\u003cp\u003eMethylation is one of the body's most fundamental biochemical processes — involved in DNA regulation, neurotransmitter synthesis, detoxification, and homocysteine metabolism. Efficient one-carbon metabolism keeps these pathways running cleanly; when it's inefficient, homocysteine can build up and impair both vascular and neurological function.\u003c\/p\u003e\n\n\u003cp\u003eThe \u003cstrong\u003eMethylation Pack\u003c\/strong\u003e was built by a physician to support this pathway directly — bioactive methylated B-vitamins, the mineral cofactors methylation enzymes require, and glutathione pathway support alongside it.\u003c\/p\u003e\n\n\u003chr\u003e\n\n\u003ch3\u003e📋 Clinical Note\u003c\/h3\u003e\n\n\u003cp\u003eThe methylation cycle converts homocysteine back to methionine using methylated folate (5-MTHF) and methylcobalamin (B12) as cofactors, with B6 supporting the alternative transsulfuration pathway that converts homocysteine to cysteine and, ultimately, glutathione. NAC directly supplies this transsulfuration pathway with a glutathione precursor. Magnesium is a required cofactor for SAM-dependent methyltransferase enzymes throughout the body. Trace minerals, particularly zinc and selenium, support additional methylation-related enzymatic activity. Vitamin D and K2 (via the ADEK complex) and omega-3 fatty acids round out the formula with complementary metabolic and anti-inflammatory support.\u003c\/p\u003e\n\n\u003chr\u003e\n\n\u003ch3\u003e🧬 What Happens When Methylation Is Inefficient\u003c\/h3\u003e\n\n\u003cul\u003e\n  \u003cli\u003e⚠️ \u003cstrong\u003eHomocysteine can build up\u003c\/strong\u003e — impairing vascular elasticity and increasing cardiovascular risk markers\u003c\/li\u003e\n  \u003cli\u003e⚠️ \u003cstrong\u003eNeurotransmitter synthesis slows\u003c\/strong\u003e — methylation is required for producing several key neurotransmitters\u003c\/li\u003e\n  \u003cli\u003e⚠️ \u003cstrong\u003eStandard folic acid and B12 aren't always usable\u003c\/strong\u003e — many people have reduced ability to convert these to their active, methylated forms\u003c\/li\u003e\n  \u003cli\u003e⚠️ \u003cstrong\u003eThe transsulfuration pathway needs support too\u003c\/strong\u003e — not just remethylation, but the route to glutathione production\u003c\/li\u003e\n  \u003cli\u003e⚠️ \u003cstrong\u003eMagnesium is a hidden requirement\u003c\/strong\u003e — methylation enzymes throughout the body depend on it as a cofactor\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eMethylation runs quietly in the background of nearly every cell. \u003cstrong\u003eThis pack supports it directly, not just the downstream symptoms of when it's not working.\u003c\/strong\u003e\u003c\/p\u003e\n\n\u003chr\u003e\n\n\u003ch3\u003e💊 Your Daily Support Pouch Contains\u003c\/h3\u003e\n\n\u003cp\u003e🌿 \u003cstrong\u003eMethyl B-Complex\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n  \u003cli\u003e5-MTHF (400mcg DFE) and Methylcobalamin B12 (500mcg) — the pre-methylated, bioactive forms that drive homocysteine remethylation\u003c\/li\u003e\n  \u003cli\u003eB6 (10mg) supports the alternative transsulfuration pathway\u003c\/li\u003e\n  \u003cli\u003eFull panel: B1 20mg, B2 17mg, B3 75mg total, Biotin 300mcg, Pantothenic Acid 50mg\u003c\/li\u003e\n  \u003cli\u003e\u003cem\u003eVegan Capsule (Hypromellose), MCT 70% C8\/C10 Coconut on Acacia | Free from: Animal Products, Wheat, Soy, Peanuts, Tree Nuts, Eggs, Milk, Shellfish, Sesame, Fish\u003c\/em\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003e🌿 \u003cstrong\u003eNAC (N-Acetyl Cysteine) — 600mg\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n  \u003cli\u003eDirectly supplies the transsulfuration pathway with a glutathione precursor\u003c\/li\u003e\n  \u003cli\u003e\u003cem\u003eCapsule: Hypromellose (Natural Vegetable), Rice Bran | Contains: Rice | Free from: Dairy, Wheat, Soy, Peanuts, Tree Nuts, Eggs, Shellfish, Sesame, Fish\u003c\/em\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003e🌿 \u003cstrong\u003eMagnesium Glycinate — 133mg\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n  \u003cli\u003eRequired cofactor for SAM-dependent methyltransferase enzymes throughout the body\u003c\/li\u003e\n  \u003cli\u003e\u003cem\u003eCapsule: Hypromellose (Vegetable), Microcrystalline Cellulose, Magnesium Stearate, Silica, Stearic Acid | Free from: Artificial Colors or Flavors, Dairy, Wheat, Soy, Peanuts, Tree Nuts, Eggs, Shellfish, Sesame, Fish\u003c\/em\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003e🌿 \u003cstrong\u003eTrace Minerals — Full Panel\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n  \u003cli\u003eIodine, Zinc, Selenium, Copper, Manganese, Chromium, Molybdenum, Potassium, Boron, Vanadium, Silica\u003c\/li\u003e\n  \u003cli\u003eZinc and selenium support additional methylation-related enzymatic activity\u003c\/li\u003e\n  \u003cli\u003e\u003cem\u003eCapsule type not specified on manufacturer label | Free from: Dairy, Wheat, Soy, Peanuts, Tree Nuts, Eggs, Shellfish, Sesame, Fish\u003c\/em\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003e🌿 \u003cstrong\u003eADEK Complex — Vitamin A, D3, E, Dual K2\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n  \u003cli\u003eVitamin D3 (125mcg\/5,000 IU) and dual-form K2 for complementary metabolic support\u003c\/li\u003e\n  \u003cli\u003e\u003cem\u003eCapsule: Hypromellose with Rice Flour, Rice Fiber, Rice Extract | Free from: Artificial colors\/flavors, Dairy, Preservatives, Wheat, Soy, Peanuts, Tree Nuts, Eggs, GMOs, Shellfish, Sesame, Fish\u003c\/em\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cem\u003eWarning: Vitamin K may interact with blood-thinning medications — consult your physician if applicable\u003c\/em\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003e🌿 \u003cstrong\u003eOmega-3 — 1000mg Fish Oil (EPA + DHA)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n  \u003cli\u003eComplementary anti-inflammatory support alongside methylation pathway function\u003c\/li\u003e\n  \u003cli\u003e\u003cem\u003eSoftgel: Gelatin with Carob color, Vegetable Glycerin, Purified Water | Contains: Fish\u003c\/em\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cstrong\u003e⚠️ Not vegan — this is the one ingredient in this pack that differs from our other vegetable-capsule formulations. Gelatin source is not specified on the manufacturer label; halal\/kosher status requires confirmation before certification claims can be made.\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003chr\u003e\n\n\u003ch3\u003e⚡ Four Pillars of Methylation Support\u003c\/h3\u003e\n\n\u003cul\u003e\n  \u003cli\u003e✅ \u003cstrong\u003eHomocysteine remethylation\u003c\/strong\u003e — Methylated 5-MTHF and B12 drive the primary methylation cycle\u003c\/li\u003e\n  \u003cli\u003e✅ \u003cstrong\u003eTranssulfuration and glutathione\u003c\/strong\u003e — B6 + NAC support the alternative pathway to glutathione\u003c\/li\u003e\n  \u003cli\u003e✅ \u003cstrong\u003eEnzymatic cofactor support\u003c\/strong\u003e — Magnesium + Trace Minerals supply what methylation enzymes require\u003c\/li\u003e\n  \u003cli\u003e✅ \u003cstrong\u003eComplementary metabolic support\u003c\/strong\u003e — ADEK + Omega-3 round out the formula\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003chr\u003e\n\n\u003ch3\u003e💡 Why This Stack Works Synergistically\u003c\/h3\u003e\n\n\u003cp\u003eThese six formulations support the methylation cycle from both branches:\u003c\/p\u003e\n\n\u003cul\u003e\n  \u003cli\u003e\n\u003cstrong\u003eMethyl B-Complex\u003c\/strong\u003e → homocysteine remethylated back to methionine using pre-activated, bioactive cofactors\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eNAC\u003c\/strong\u003e → the transsulfuration branch supplied directly with a glutathione precursor\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eMagnesium + Trace Minerals\u003c\/strong\u003e → the enzymatic cofactors methylation reactions depend on, throughout the body\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eADEK + Omega-3\u003c\/strong\u003e → complementary metabolic and anti-inflammatory support\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eThis isn't a basic B12 gummy. This isn't guesswork.\u003c\/p\u003e\n\u003cp\u003eThis is \u003cstrong\u003ephysician-formulated methylation support\u003c\/strong\u003e — addressing both branches of homocysteine metabolism, not just one.\u003c\/p\u003e\n\n\u003chr\u003e\n\n\u003ch3\u003e🔬 Full Transparency — Verified Supplement Facts\u003c\/h3\u003e\n\n\u003ctable\u003e\n  \u003cthead\u003e\n    \u003ctr\u003e\n      \u003cth\u003eIngredient\u003c\/th\u003e\n      \u003cth\u003eDose\u003c\/th\u003e\n      \u003cth\u003eCapsule Type\u003c\/th\u003e\n      \u003cth\u003ePurpose\u003c\/th\u003e\n    \u003c\/tr\u003e\n  \u003c\/thead\u003e\n  \u003ctbody\u003e\n    \u003ctr\u003e\n      \u003ctd\u003eMethyl B-Complex\u003c\/td\u003e\n      \u003ctd\u003e\u003cstrong\u003eFull B panel\u003c\/strong\u003e\u003c\/td\u003e\n      \u003ctd\u003eVegan Capsule (Hypromellose)\u003c\/td\u003e\n      \u003ctd\u003eHomocysteine remethylation\u003c\/td\u003e\n    \u003c\/tr\u003e\n    \u003ctr\u003e\n      \u003ctd\u003eNAC\u003c\/td\u003e\n      \u003ctd\u003e\u003cstrong\u003e600mg\u003c\/strong\u003e\u003c\/td\u003e\n      \u003ctd\u003eHypromellose (Vegetable)\u003c\/td\u003e\n      \u003ctd\u003eTranssulfuration, glutathione\u003c\/td\u003e\n    \u003c\/tr\u003e\n    \u003ctr\u003e\n      \u003ctd\u003eMagnesium Glycinate\u003c\/td\u003e\n      \u003ctd\u003e\u003cstrong\u003e133mg\u003c\/strong\u003e\u003c\/td\u003e\n      \u003ctd\u003eHypromellose (Vegetable)\u003c\/td\u003e\n      \u003ctd\u003eMethyltransferase cofactor\u003c\/td\u003e\n    \u003c\/tr\u003e\n    \u003ctr\u003e\n      \u003ctd\u003eTrace Minerals\u003c\/td\u003e\n      \u003ctd\u003e\u003cstrong\u003eFull panel\u003c\/strong\u003e\u003c\/td\u003e\n      \u003ctd\u003eNot specified on label\u003c\/td\u003e\n      \u003ctd\u003eEnzymatic cofactors\u003c\/td\u003e\n    \u003c\/tr\u003e\n    \u003ctr\u003e\n      \u003ctd\u003eADEK Complex\u003c\/td\u003e\n      \u003ctd\u003e\u003cstrong\u003eA, D3, E, dual K2\u003c\/strong\u003e\u003c\/td\u003e\n      \u003ctd\u003eHypromellose (Rice-based)\u003c\/td\u003e\n      \u003ctd\u003eMetabolic support\u003c\/td\u003e\n    \u003c\/tr\u003e\n    \u003ctr\u003e\n      \u003ctd\u003eOmega-3 Fish Oil\u003c\/td\u003e\n      \u003ctd\u003e\u003cstrong\u003e1000mg\u003c\/strong\u003e\u003c\/td\u003e\n      \u003ctd\u003eGelatin (source unspecified)\u003c\/td\u003e\n      \u003ctd\u003eAnti-inflammatory support\u003c\/td\u003e\n    \u003c\/tr\u003e\n  \u003c\/tbody\u003e\n\u003c\/table\u003e\n\n\u003cbr\u003e\n\n\u003cul\u003e\n  \u003cli\u003e✅ \u003cstrong\u003eNo proprietary blends\u003c\/strong\u003e — every dose verified and disclosed\u003c\/li\u003e\n  \u003cli\u003e✅ \u003cstrong\u003ePhysician-formulated\u003c\/strong\u003e — not assembled by a marketing team\u003c\/li\u003e\n  \u003cli\u003e✅ \u003cstrong\u003e5 of 6 ingredients use vegetable-based capsules\u003c\/strong\u003e — no gelatin, no animal-derived shells\u003c\/li\u003e\n  \u003cli\u003e⚠️ \u003cstrong\u003eOmega-3 is the exception\u003c\/strong\u003e — gelatin softgel, contains fish. Not vegan. Halal\/kosher status pending gelatin source confirmation.\u003c\/li\u003e\n  \u003cli\u003e✅ \u003cstrong\u003eFree from (except Omega-3):\u003c\/strong\u003e Wheat, Soy, Dairy, Peanuts, Tree Nuts, Eggs, Shellfish, Sesame, GMOs, Artificial Colors \u0026amp; Flavors\u003c\/li\u003e\n  \u003cli\u003e✅ \u003cstrong\u003ecGMP certified facility\u003c\/strong\u003e — manufactured to pharmaceutical standards\u003c\/li\u003e\n  \u003cli\u003e✅ \u003cstrong\u003eThird-party tested\u003c\/strong\u003e — purity and potency verified\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003chr\u003e\n\n\u003ch3\u003e🕌 Dietary \u0026amp; Religious Compliance\u003c\/h3\u003e\n\n\u003cp\u003eFive of six formulations in this pack use vegetable-based capsules with zero animal-derived gelatin. \u003cstrong\u003eThe Omega-3 softgel is the exception\u003c\/strong\u003e — gelatin source not specified on label, contains fish. This means the pack cannot currently be certified vegan, and halal\/kosher status depends on confirming the gelatin's origin with the manufacturer.\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eWe believe in disclosing this clearly rather than making a claim we can't fully back. Always consult your religious authority for final certification guidance.\u003c\/em\u003e\u003c\/p\u003e\n\n\u003chr\u003e\n\n\u003ch3\u003e⚠️ Suggested Use\u003c\/h3\u003e\n\n\u003cp\u003eTake all capsules in your daily pouch each morning, preferably with or after breakfast. Consult your healthcare provider before starting any supplement regimen, especially if you are taking blood-thinning medication, have known MTHFR gene variants, or are managing a medical condition.\u003c\/p\u003e\n\n\u003chr\u003e\n\n\u003ch3\u003e🏆 Perfect For\u003c\/h3\u003e\n\n\u003cul\u003e\n  \u003cli\u003eIndividuals with known MTHFR gene variants who need pre-methylated B-vitamins\u003c\/li\u003e\n  \u003cli\u003eAnyone whose bloodwork has shown elevated homocysteine\u003c\/li\u003e\n  \u003cli\u003eThose interested in supporting detoxification, neurotransmitter synthesis, and cardiovascular health through methylation pathway support\u003c\/li\u003e\n  \u003cli\u003e\u003cem\u003eNote: pescatarians are fine with this pack; strict vegans or those requiring certified halal\/kosher gelatin should contact us before ordering\u003c\/em\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003chr\u003e\n\n\u003ch3\u003e📦 Pack Details\u003c\/h3\u003e\n\n\u003cul\u003e\n  \u003cli\u003e✅ \u003cstrong\u003e6 formulations\u003c\/strong\u003e per daily pouch\u003c\/li\u003e\n  \u003cli\u003e✅ \u003cstrong\u003e30-day supply\u003c\/strong\u003e — one pouch per day\u003c\/li\u003e\n  \u003cli\u003e✅ \u003cstrong\u003eAM delivery recommended\u003c\/strong\u003e — take with or after breakfast\u003c\/li\u003e\n  \u003cli\u003e✅ \u003cstrong\u003e80% less plastic\u003c\/strong\u003e than traditional supplement bottles\u003c\/li\u003e\n  \u003cli\u003e✅ \u003cstrong\u003eShips from Las Vegas, NV\u003c\/strong\u003e in 2–5 business days\u003c\/li\u003e\n  \u003cli\u003e✅ \u003cstrong\u003eEco-friendly packaging\u003c\/strong\u003e — physician-branded, professionally labeled\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003chr\u003e\n\n\u003cp\u003e\u003cem\u003eScience-backed. Physician-formulated. Fully transparent. Pouch-delivered.\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eTear. Take. Feel the difference. 💪\u003c\/strong\u003e\u003c\/p\u003e","brand":"Dad Puzzles EDGE","offers":[{"title":"Default Title","offer_id":47577613861123,"sku":"00000000-00000000-00000000-00000000","price":84.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0793\/4997\/3251\/files\/methylation.png?v=1766613986","url":"https:\/\/dadpuzzlesedge.com\/products\/methylation-pack","provider":"Dadpuzzles Edge","version":"1.0","type":"link"}